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Textbook of Small Animal Pathophysiology
Stephan Neumann ISBN: 9781119824619 August 2024 Wiley-Blackwell 560 pages
Description
The comprehensive overview of the essential discipline of pathophysiology in small animal disease
Textbook of Small Animal Pathophysiology provides a complete and accessible overview of disease mechanisms and pathophysiological consequences in the field of small animal medicine. The text focuses on the relationship between pathophysiology and disease of any etiology to aid better diagnostics and targeted therapy.
The text includes general pathophysiology of key organ systems such as cardiac, respiratory, gastrointestinal, neural, and more. Core information such as diagnostic methods and therapeutic options is presented in tabular form and clear full-color illustrations are featured throughout to aid in seamless reader comprehension.
Written by a highly qualified professional with significant firsthand experience in the field, Textbook of Small Animal Pathophysiology includes information on:
Common pathological mechanisms, such as inflammation, sepsis and cytokine storm, fibrosis, degeneration, obesity, ischemia, hypoxia, cell death, apoptosis, necrosis, neoplasia, infection, ageing and pain
General clinical manifestations, like abdominal enlargement, ataxia, constipation, cough, diarrhea, dyschezia, dysphagia, dyspnea, effusion, fatigue, fever, inappetence, jaundice, oedema, polyphagia, pruritus, regurgitation, seizure, shock, syncope, urinary disorders, vomitus, and weight loss
Pathophysiology of organ systems cardiac system, hypertension, respiratory system, gastrointestinal system, hepatobiliary system, exocrine pancreas, urinary system, electrolyte system and acid-base balance, endocrine system, reproduction system, nerve system, joints, haematology and infectious diseases
Written to be a complete resource on the subject, Textbook of Small Animal Pathophysiology enables its readers to develop a clear understanding of how each disease works in order to improve decision making and patient outcomes. It is essential reading for veterinary students and a highly useful reference for small animal clinicians.
Table of Contents
Preface x Abbreviations xii
Part I General Pathological Mechanisms 1
1 Inflammation 3
2 Sepsis and Cytokine Storm 14
3 Fibrosis 19
4 Degeneration 24
5 Obesity 27
6 Ischaemia, Hypoxia 32
7 Cell Death 36
8 Neoplasia 40
9 Infections 46
10 Ageing 53
11 Pain 58
12 Hypothalamus Function 61
Part II General Clinical Manifestations (Alphabetical) 65
13 Abdominal Enlargement 67
14 Ataxia 70
15 Constipation 74
16 Cough 78
17 Diarrhoea 81
18 Dyschezia 87
19 Dysphagia 90
20 Dyspnoea 93
21 Effusions 97
22 Fatigue 104
23 Fever 106
24 Inappetence 110
25 Jaundice 113
26 Oedema 116
27 Polyphagia 119
28 Pruritus 122
29 Regurgitation 124
30 Seizure 126
31 Shock 130
32 Syncope 133
33 Urinary Disorders 138
34 Vomiting 143
35 Weight Loss 147
Part III Pathophysiology of Organ Systems 151 36 Cardiac System, Hypertension 153 36.1 Physiological Functions and General Pathophysiology of Organ Insufficiency 153 36.2 Congenital Cardiac Diseases 161 36.3 Atrioventricular Valvular Diseases 167 36.4 Cardiomyopathy, Hypertrophic 172 36.5 Cardiomyopathy, Dilated 176 36.6 Heart Arrhythmia 181 36.7 Pericardial Disease 184 36.8 Hypertension 190
37 Respiratory System 195 37.1 Physiological Functions and General Pathophysiology of Organ Insufficiency 195 37.2 Brachiocephalic Syndrome 200 37.3 Acute Respiratory Distress Syndrome (ARDS) 203 37.4 Asthma (Feline Lower Respiratory Tract Disease) 207 37.5 Chronic Obstructive Bronchitis 210 37.6 Pneumonia 21 37.7 Idiopathic Lung Fibrosis 217
38 Gastrointestinal System 220 38.1 Physiological Functions and General Pathophysiology of Organ Insufficiency 220 38.2 Megaoesophagus 226 38.3 Gastritis/Ulceration 229 38.4 Gastric Dilatation-Volvulus Syndrome 233 38.5 Enteritis/Inflammatory Bowel Disease 237 38.6 Intestinal Lymphangiectasias 243 38.7 Intestinal Obstruction 249
39 Hepatobiliary System 253 39.1 Physiological Functions and General Pathophysiology of Organ Insufficiency 253 39.2 Acute Hepatic Failure 261 39.3 Chronic Hepatitis; Liver Fibrosis and Cirrhosis 266 39.4 Portosystemic Shunts/Hepatoencephalopathy 272 39.5 Feline Hepatic Lipidosis 277 39.6 Cholangiohepatitis 280
40 Exocrine Pancreas 284 40.1 Physiological Functions and General Pathophysiology of Organ Insufficiency 284 40.2 Acute Pancreatitis 287 40.3 Chronic Pancreatitis 292 40.4 Exocrine Pancreas Insufficiency 296
41 Urinary System 300 41.1 Physiological Functions of the Kidneys and General Pathophysiology of Organ Insufficiency 300 41.2 Glomerulonephritis/Nephrotic Syndrome 305 41.3 Tubular Disease/Fanconi Syndrome 310 41.4 Acute Renal Failure 313 41.5 Chronic Kidney Disease 321 41.6 Urinary Tract Infection 327 41.7 Urolithiasis 330
42 Electrolyte System and Acid-Base Balance 335 42.1 Acid-Base Balance 335 42.2 Hypo-/Hypernatraemia 340 42.3 Hypo-/Hyperkalaemia 344
43 Endocrine System 349 43.1 General Physiology 349 43.2 Pituitary Gland 352 43.2.1 Acromegaly 352 43.2.2 Pituitary Dwarfism 356 43.2.3 Diabetes Insipidus 359 43.3 Thyroid Gland 362 43.3.1 Physiology of the Thyroid Gland 362 43.3.2 Hyperthyroidism 365 43.3.3 Hypothyroidism 369 43.4 Parathyroid Gland 374 43.5 Endocrine Pancreas 379 43.5.1 Physiology of Endocrine Pancreas 379 43.5.2 Diabetes Mellitus 382 43.5.3 Diabetic Ketoacidosis 387 43.5.4 Insulinoma 390 43.6 Adrenal Gland 393 43.6.1 Physiology of the Adrenal Gland 393 43.6.2 Hyperadrenocorticism 397 43.6.3 Hypoadrenocorticism 402 43.6.4 Hyperaldosteronism 405 43.6.5 Pheochromocytoma 409
44 Reproduction System 413 44.1 Pyometra 413 44.2 Prostate Diseases 417
45 Nerve System 420 45.1 Brain Tumours 420 45.2 Idiopathic Epilepsy 423 45.3 Intervertebral Disc Disease 426 45.4 Peripheral Neuropathy 429
46 Joints 431 46.1 Arthritis 431 46.2 Osteoarthritis 434
47 Haematology 437 47.1 Physiological Functions of Red Blood Cells 437 47.2 Erythrocytosis 441 47.3 Anaemia 444 47.4 Coagulation Disorders 450 47.5 Hypercoagulability 454
48 Infectious Diseases 457 48.1 Feline 457 48.1.1 Feline Leukaemia Virus Infection 457 48.1.2 Feline Infectious Peritonitis 461 48.1.3 Feline Immunodeficiency Virus Infection 466 48.2 Canine 471 48.2.1 Distemper 471 48.2.2 Canine Parvovirus 475 48.3 Bacterial Diseases 480 48.3.1 Anaplasmosis 480 48.3.2 Borreliosis 484 48.3.3 Ehrlichiosis 488 48.3.4 Leptospirosis 491 48.4 Protozoal Infections 495 48.4.1 Babesiosis 495 48.4.2 Giardiasis 499 48.4.3 Leishmaniasis 503 49 Common Immune-mediated Diseases 507 49.1 Autoimmunity 507 49.2 Lupus Erythematosus 510 49.3 Myasthenia Gravis 514
50 Common Clinical Biochemical Parameters (Alphabetical) 517 50.1 Alanine Aminotransferase (ALT) 517 50.2 Albumin 518 50.3 Alkaline Phosphatase (ALP) 520 50.4 Ammonia 522 50.5 Aspartate Aminotransferase (AST) 523 50.6 Bile Acids 524 50.7 Bilirubin 525 50.8 Calcium 526 50.9 Cholesterol 528 50.10 Creatinine 529 50.11 Creatine Kinase 530 50.12 Glucose 531 50.13 Glutamate Dehydrogenase (GLDH) 532 50.14 Lipase 533 50.15 Phosphorus 534 50.16 Potassium 535 50.17 Sodium 537 50.18 Total Protein 539 50.19 Urea 541 Index 542
About the Author
Stephan Neumann Prof. Dr. med. vet. is Clinical Director of the Small Animal Clinic and apl. Prof. at the University of Göttingen, Germany.
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