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공중보건/전염병학 > 공중보건 > Fenner and White's Medical Virology, 5th Edition

 
Fenner and White's Medical Virology, 5th Edition
상품명 : Fenner and White's Medical Virology, 5th Edition
제조회사 : Academic Press
원산지 : UK
적립금액 : 5,370원
소비자가 : 179,000원
판매가격 : 179,000원
수량 EA
 
배송조건 : (조건)
   
 

Fenner and White's Medical Virology, 5th Edition



Authors: Christopher Burrell Colin Howard Frederick Murphy                  

ISBN: 9780123751560
Imprint: Academic Press
Published Date: 30th November 2016
Page Count: 604


Description

Fenner and White's Medical Virology, Fifth Edition provides an integrated view of related sciences, from cell biology, to medical epidemiology and human social behavior. The perspective represented by this book, that of medical virology as an infectious disease science, is meant to provide a starting point, an anchor, for those who must relate the subject to clinical practice, public health practice, scholarly research, and other endeavors.

The book presents detailed exposition on the properties of viruses, how viruses replicate, and how viruses cause disease. These chapters are then followed by an overview of the principles of diagnosis, epidemiology, and how virus infections can be controlled. The first section concludes with a discussion on emergence and attempts to predict the next major public health challenges.

These form a guide for delving into the specific diseases of interest to the reader as described in Part II. This lucid and concise, yet comprehensive, text is admirably suited to the needs of not only advanced students of science and medicine, but also postgraduate students, teachers, and research workers in all areas of virology.



Key Features


  • Features updated and expanded coverage of pathogenesis and immunity
  • Contains the latest laboratory diagnostic methods
  • Provides insights into clinical features of human viral disease, vaccines, chemotherapy, epidemiology, and control



    • Table of Contents


    Dedication

  • Foreword
  • Preface
  • Part I: Principles of Virology        

    Chapter 1. History and Impact of Virology        

  • Abstract

    Why Study Virology?

    A Brief History of Virology

    The Virosphere

    The Nature of Viruses

    Scope of This Book

    Further Reading


  • Chapter 2. Classification of Viruses and Phylogenetic Relationships

    Abstract

    Viral Taxonomy

    Viral Nomenclature

    Groupings of Viruses on the Basis of Epidemiological Criteria

    Taxonomy and the Causal Relationship between Virus and Disease

    Genome Sequencing and Virus Evolution

    Further Reading


  • Chapter 3. Virion Structure and Composition

    Abstract

    Physical Methods for Studying Virus Structure

    Chemical Composition of Virions

    Virion Symmetry

    Further Reading


  • Chapter 4. Virus Replication

    Abstract

    Growth of Viruses

    The Virus Replication Cycle

    Satellite Viruses and Viroids

    Generation of Genetic Diversity

    Quantitative Virus Assays

    Defective Interfering Viruses

    Further Reading


  • Chapter 5. Innate Immunity

    Abstract

    Innate Responses

    Monocytes, Macrophages, and Dendritic Cells

    The Role of Natural Killer (NK) Cells and the Link with Adaptive Immunity

    The Importance of Molecular Recognition

    Interferons

    Cell Death and Apoptosis

    Evasion Strategies

    Further Reading


  • Chapter 6. Adaptive Immune Responses to Infection

    Abstract

    Overview of the Adaptive Immune Responses to Viral Infection

    The Major Histocompatibility Complex (MHC) and Antigen Presentation

    Antibodies

    Cytokines

    Recovery from Viral Infection

    Neutralization of Viral Infectivity by Antibodies

    Immunity to Reinfection

    Immunological Memory

    Further Reading


  • Chapter 7. Pathogenesis of Virus Infections

    Abstract

    The Incoming Virus Inoculum

    Routes of Entry—A Major Factor Governing the Specific Pattern of Infection

    Mechanisms of Virus Spread Within the Body

    Virus Infection of Target Organs

    Persistent Virus Infections—Mechanisms Influencing Persistence

    Mechanisms of Disease Production

    Viruses and Immunosuppression

    Viral Virulence and Host Resistance to Infection

    Co-infections

    Further Reading


  • Chapter 8. Patterns of Infection

    Abstract

    Transient Localized Infections

    Transient Systemic Infections

    Persistent Infections

    Persistent Localized Infections

    Persistent Systemic Infections

    Further Reading


  • Chapter 9. Mechanisms of Viral Oncogenesis

    Abstract

    Definitions and Overview of Virus Transformation

    Oncogenes and Tumor Suppressor Genes

    Oncogenesis by Retroviruses

    Oncogenesis by Small DNA Viruses

    Oncogenesis by Large DNA Viruses

    Other Important Viruses Associated with Cancers

    The Prevention and Management of Virally Induced Tumors

    Further Reading


  • Chapter 10. Laboratory Diagnosis of Virus Diseases

    Abstract

    Rationale for Performing Laboratory Virus Diagnosis

    Collection, Packaging, and Transport of Samples

    Direct Identification of Virus, Viral Antigen, or Viral Genome

    Virus Isolation

    Measurement of Serum Antibodies

    Interpretation of Laboratory Results

    Laboratory Safety

    Further Reading


  • Chapter 11. Vaccines and Vaccination

    Abstract

    Vaccine Design and Production

    Vaccine Safety, Efficacy, and Practical Usage

    Factors Affecting Vaccine Safety

    Passive Protection

    Vaccination Policy and Programs

    Further Reading


  • Chapter 12. Antiviral Chemotherapy

    Abstract

    Strategies for the Development of AntiViral Agents

    Clinical Application

    Clinical Strategies

    Mechanisms of Action and Role of Individual AntiViral Drugs

    Newer Approaches Under Development

    Further Reading


  • Chapter 13. Epidemiology of Viral Infections

    Abstract

    Mechanisms of Virus Survival

    Viral Shedding and Routes of Transmission

    Factors Affecting the Dynamics of Viral Infections

    Epidemiological Investigations

    Mathematical Modeling

    Further Reading


  • Chapter 14. Control, Prevention, and Eradication

    Abstract

    Surveillance and Modeling of Virus Diseases

    Measures to Minimize Transmission

    Immunization

    Eradication

    Bioterrorism

    Further Reading


    • Chapter 15. Emerging Virus Diseases

    Abstract

    Increased Recognition and Changes in Disease Patterns

    Factors Affecting Emergence

    Climate Change

    Ease of Travel

    Animals as a Source of Human Diseases

    Prevention and Control

    Further Reading

    Part II: Specific Virus Diseases of Humans


    Chapter 16. Poxviruses

    Abstract

    Properties of Poxviruses

    Diseases Caused by Members of the Genus Orthopoxvirus

    Diseases Caused by Members of the Genus Molluscipoxvirus

    Diseases Caused by Members of the Genus Yatapoxvirus

    Diseases Caused by Members of the Genus Parapoxvirus

    Further Reading


    Chapter 17. Herpesviruses

    Abstract

    Properties of the Viruses

    Herpes Simplex Virus Infection

    Varicella-Zoster Virus Infection

    Cytomegalovirus Infection

    Human Herpesviruses 6 and 7 (HHV-6 and HHV-7) Infection

    Epstein-Barr Virus Infection

    Human Herpesvirus 8 (HHV-8: Kaposi’s Sarcoma-Associated Herpesvirus) Infection

    B Virus (Macacine Herpesvirus 1) Infection

    Further Reading


    Chapter 18. Adenoviruses

    Abstract

    Classification

    Properties of Adenoviruses

    Virus Replication

    Adenovirus Diseases

    Pathogenesis, Pathology, and Immunity

    Laboratory Diagnosis

    Epidemiology, Prevention, Control, Treatment

    Adenoviruses as Vectors for the Delivery of Heterologous DNA

    Further Reading


    Chapter 19. Papillomaviruses

    Abstract

    Classification

    Properties of Papillomaviruses

    Viral Replication

    Clinical Feature

    Pathogenesis and Immunity

    Natural History of Genital HPV Infection

    Laboratory Diagnosis

    Epidemiology

    Treatment and Prevention

    Further Reading


    Chapter 20. Polyomaviruses

    Abstract

    Classification, Properties, and Replication

    Pathogenesis

    BK Polyomavirus

    JC Polyomavirus

    Other Recently Described Human Polyomaviruses

    Further Reading


    Chapter 21. Parvoviruses

    Abstract

    Classification

    Properties of Parvoviridae

    Viral Replication

    Parvovirus B19

    Pathogenesis and Immunity

    Clinical Features

    Transient Aplastic Crisis

    Other Complications of Parvovirus B19 Infection

    Laboratory Diagnosis

    Epidemiology

    Treatment and Control

    Dependoviruses

    Human Bocaviruses

    Further Reading


    Chapter 22. Hepatitis B and Hepatitis Delta Viruses

    Abstract

    Hepatitis B Virus

    Hepatitis Delta Virus

    Classification

    Virion Properties

    Viral Replication

    Clinical Features

    Pathogenesis

    Laboratory Diagnosis

    Epidemiology

    Treatment and Prevention

    Further Reading


    Chapter 23. Retroviruses

    Abstract

    Properties of Retroviridae

    Viral Replication

    Human T cell Lymphotropic Viruses

    Human Immunodeficiency Viruses

    Subfamily Spumavirinae

    Further Reading


    Chapter 24. Reoviruses

    Abstract

    Properties of Reoviruses

    Viral Replication

    Rotavirus Gastroenteritis

    Orbiviruses

    Coltiviruses

    Orthoreoviruses

    Further Reading


    Chapter 25. Orthomyxoviruses

    Abstract

    Properties of Orthomyxoviruses

    Influenza

    Further Reading


    Chapter 26. Paramyxoviruses

    Abstract

    Properties of Paramyxoviruses

    Respiratory Syncytial Virus Infection

    Parainfluenza Virus Infections

    Human Metapneumovirus Infection

    Measles

    Mumps

    Henipavirus Infections

    Further Reading


    Chapter 27. Rhabdoviruses

    Abstract

    Properties of Rhabdoviruses

    Rabies

    Vesicular Stomatitis and Other Rhabdoviruses

    Further Reading


    Chapter 28. Filoviruses

    Abstract

    Properties of Bunyaviruses

    Ebola and Marburg Virus Disease (Ebola and Marburg Hemorrhagic Fever)

    Further Reading


    Chapter 29. Bunyaviruses

    Abstract

    Properties of Bunyaviruses

    Diseases Caused by Members of the Genus Orthobunyavirus

    Diseases Caused by Members of the Genus Phlebovirus

    Diseases Caused by Members of the Genus Nairovirus

    Diseases Caused by Members of the Genus Hantavirus

    Further Reading


    Chapter 30. Arenaviruses

    Abstract

    Properties of Arenaviruses

    Lymphocytic Choriomeningitis Virus Infection

    Lassa Fever

    Lujo Virus Infection

    South American Hemorrhagic Fevers

    Further Reading


    Chapter 31. Coronaviruses

    Abstract

    Properties of Coronaviruses

    Human Coronavirus Infections

    Severe Acute Respiratory Virus (SARS-CoV)

    Middle East Respiratory Virus (MERS-CoV)

    Further Reading


    Chapter 32. Picornaviruses

    Abstract

    Properties of Picornaviruses

    Poliomyelitis

    Enteroviruses A, B, C, D, and Parechoviruses

    Human Rhinoviruses A, B, and C

    Hepatitis A (HAV)

    Further Reading


    Chapter 33. Caliciviruses

    Abstract

    Classification

    Virion Properties

    Calicivirus (Norovirus and Sapovirus) Gastroenteritis

    Further Reading


    Chapter 34. Astroviruses

    Abstract

    Properties of Astroviruses

    Clinical Features

    Laboratory Diagnosis

    Epidemiology

    Prevention

    Further Reading


    Chapter 35. Togaviruses

    Abstract

    Properties of Togaviruses

    Diseases Caused by Members of the Genus Alphavirus

    Alphaviruses Causing Encephalitis—Eastern, Western, and Venezuelan Encephalitis

    Alphavirus Infections Marked by Fever, Rash, Myalgia, Arthralgia, and Arthritis

    Chikungunya

    Other Alphavirus Infections

    Disease Caused by the Rubivirus Rubella Virus

    Further Reading


    Chapter 36. Flaviviruses

    Abstract

    Properties of Flaviviruses

    Diseases Caused by Mosquito-Borne Member Viruses of the Genus Flavivirus

    Yellow Fever

    Dengue

    Zika Virus

    Japanese Encephalitis

    West Nile Virus Infection

    St. Louis Encephalitis

    Usutu Virus Infection

    Murray Valley (Australian) Encephalitis

    Rocio Virus Encephalitis

    Diseases Caused by Tick-Borne Members of the Genus Flavivirus

    Diseases Caused by Members of the Genus Hepacivirus

    Other Hepaciviruses

    Further Reading


    Chapter 37. Hepeviruses

    Abstract

    Classification and Properties of Hepatitis E Virus

    Viral Replication

    Clinical Features

    Pathology, Pathogenesis, and Immunity

    Laboratory Diagnosis

    Epidemiology, Prevention, Control, and Therapeutics

    Further Reading


    Chapter 38. Prions

    Abstract

    Properties of Prions

    Human Prion Diseases

    Diagnosis

    Treatment and Prevention

    Other Chronic Neurodegenerative Diseases

    Further Reading


    Chapter 39. Viral Syndromes

    Abstract

    The Human Virome

    Viral Diseases of the Respiratory Tract

    Viral Gastroenteritis

    Viral Diseases of the Central Nervous System

    Viral Skin Rashes

    Viral Hemorrhagic Fevers

    Viral Genitourinary Infections

    Viral Diseases of the Eye

    Viral Arthritis

    Viral Carditis

    Viral Hepatitis

    Viral Pancreatitis and Diabetes

    Chronic Fatigue Syndrome

    Congenital and Perinatal Viral Infections

    Viral Infections in Immunocompromised Patients

    Diseases of Unknown Etiology

    Further Reading

    Index



    About the Author



    Christopher Burrell

    AO, BSc(Med), MBBS, PhD, FRCPath, FRCPA. Emeritus Professor of Virology, University of Adelaide, and former Head of the Infectious Diseases Laboratories, Institute of Medical and Veterinary Science, Adelaide, South Australia, Australia. His research expertise lies in hepatitis viruses particularly hepatitis B; HIV and AIDS; influenza; virus diagnosis and pathogenesis; immunization and prevention of virus infections. For more than forty years he has taught medical undergraduates and graduates and doctoral students, and worked with government research funding and public health bodies.


    Colin Howard

    Colin R Howard, DSc, PhD, FRCPath, FRSB holds professorships at London and Birmingham Universities. With over 40 years of experience in research and the teaching of virology, he has taught workshops to undergraduates, veterinarians and postgraduate health care workers in Europe, Asia, Africa and the Americas. His research interests are focused on persistent virus infections and haemorrhage fevers. Through his interest in vaccines he has advised the World Health Organisation, government agencies and vaccine manufacturers.

     
     
     
     
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