The IACUC Handbook, Third Edition
Author : Jerald Silverman, Mark Suckow, Sreekant Murthy
Imprint : CRC Press
Release Date : May 20, 2014
ISBN : 9781466555648
Pages : 827 Pages
Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare oversight within research institutions in the United States. As biomedical research continuously grows, the role and impact of the IACUC has increased in scope and complexity. The IACUC Handbook has become "the Bible" for individuals when the time comes for them to serve on their institution’s IACUC. It provides a foundation for understanding and implementing the many and varied responsibilities of this committee.
This Third Edition comprehensively addresses the significant changes in the pertinent regulatory environment and interpretation of applicable federal laws, regulations, and policies. It provides multiple references and commentary on the new edition of the Guide for the Care and Use of Laboratory Animals, the new AVMA Guidelines for the Euthanasia of Animals: 2013 Edition, and the Office of Laboratory Animal Welfare’s Frequently Asked Questions. The Third Edition also features an updated survey of IACUC practices from institutions around the United States, offering wisdom gained from their experience. In addition, it includes a chapter that provides an international perspective on how animal welfare reviews can function in other countries.
Table of Contents
Introduction to the Third EditionPatricia A. Brown and Chester A. GipsonOrigins of the IACUCHarry RozmiarekCircumstances Requiring an IACUCMarcy Brown and Mary Jo ShepherdCreation of an IACUCMarcy Brown and Mary Jo ShepherdReporting Lines of the IACUCMarcy Brown and Mary Jo ShepherdGeneral Composition of the IACUC and Specific Roles of the IACUC MembersChristian E. Newcomer and William G. GreerFrequency and Conduct of Regular IACUC MeetingsSreekant MurthyGeneral Format of IACUC Protocol FormsChristian E. Newcomer and William G. GreerSubmission and Maintenance of IACUC ProtocolsKathy Laber and Alison C. SmithGeneral Concepts of Protocol ReviewErnest D. Prentice, Gwenn S. F. Oki, and Michael D. MannAmending IACUC ProtocolsAngela M. Mexas and Diane J. GaertnerContinuing Review of ProtocolsGwenn S.F. Oki and Ernest D. PrenticeJustification for the Use of AnimalsLarry CarboneJustification of the Number of Animals to Be UsedEd J. GracelyAnimal Acquisition and DispositionMichael J. Huerkamp, Larry Iten, and David R. ArcherAnimal Housing, Use Sites, and TransportationRobert M. Bigsby and Robin Crisler-RobertsPain and DistressAlicia Z. Karas and Jerald SilvermanEuthanasiaPeggy J. DannemanSurgeryLester L. Rolf, Jr.Antigens, Antibodies, and Blood CollectionHarold F. Stills, Jr.Occupational Health and SafetyRobin Lyn Trundy and Susan Stein CookPersonnel TrainingHoward G. Rush and Melissa C. DysonConfidential and Proprietary InformationMarilyn J. Chimes and Priya SankarGeneral Concepts of the Program Review and Facility InspectionJoseph D. Thulin and Kenneth P. AllenInspection of Animal Housing AreasChristine A. Boehm and Debra L. HickmanInspection of Individual LaboratoriesNeil S. Lipman and Scott E. PerkinsInspection of Surgery AreasScott E. Perkins and Neil S. LipmanAssessment of Veterinary CareMark A. Suckow and Bernard J. DoerningLaboratory Animal EnrichmentKathryn Bayne and Jennifer N. CamachoAnimal Mistreatment and Protocol NoncomplianceJerald SilvermanPostapproval MonitoringRon E. BanksThe European Ethical Review Framework: Collaborative IssuesJavier Guillén