Reflects updates to new tumor staging data in the American Joint Committee on Cancer (AJCC) 8th Edition and updated ASCO/CAP guidelines for interpreting HER2 assays 

Brings you fully up to date with recent advances, including new molecular information for breast entities, new surgical techniques, more widely used multigene prognostic tests, and assays used to determine treatment, such as PD-L1 as a new immunotherapy biomarker for triple-negative breast cancer 

Features new chapters covering gene expression profiling; immunotherapy; the differential diagnosis for common histologic patterns; solid papillary carcinoma; acinic cell carcinoma; and intraoperative consultations, including a video showing how to process specimens with radioactive seeds 

Offers expert guidance on evaluation of postneoadjuvant resection specimens, sentinel lymph nodes, and extent of disease and multifocality 

Contains thousands of extensively annotated images, including gross pathology photographs, histopathology photomicrographs with a wide range of immunohistochemical stains, fluorescent in situ hybridization, and full-color illustrations 

Features a templated, highly formatted design; concise, bulleted text; diagnostic pearls; key facts in each chapter; and an extensive index for easy reference 

Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices