Diagnostic Pathology: Infectious Diseases, 3rd Edition

Main Author : By Isaac H. Solomon, MD, PhD and Dan Milner, MD, MSc(Epi), MBA

ISBN : 9780443124778

Trim : 216w x 276h

Imprint : Elsevier

Publication Date : Dec 2023

Page : 560

Description

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of infectious diseases, including novel infections and lesser-known microorganisms, this volume incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Infectious Diseases is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.

New to this edition

Expanded text throughout the 3rd edition, including Expanded introductory section with -Updated biosafety chapter (issues in frozen section room, gross room, and at autopsy)-Novel/emerging diagnostic techniques (whole slide imaging with AI; mass spec imaging, metagenomic next gen sequencing-Chapters on most >> least common infections of CNS, head & neck, skin/soft tissue, pulmonary, cardiac, GI, GU, and GYN systems plus best approach for diagnostic work upNew or split/expanded existing chapters for specific infections, including-COVID-19: acute and post-acute infections, variants of concern, effect on all organ systems-Monkeypox-Separate Burili ulcer (Mycobacterium ulcerans infection)-Separate Burili ulcer (Mycobacterium ulcerans infection)4 NEW additional nematode chapters3 NEW additional trematode chapters2 NEW additional cestode chapters Additional NEW fungal chapters which include culture plate, lactophenol blue, and cytology images for eachNEW detailed tick identification chapter

Key Features

• Covers all areas of infectious disease pathology, including infections of the central nervous system, head and neck, and skin/soft tissue as well as the pulmonary, cardiac, gastrointestinal, genitourinary, and gynecologic systems

• Includes new chapters on COVID-19 and mpox, nine new helminth chapters, additional new fungal chapters, an updated biosafety chapter, and more

• Contains significantly updated information throughout, including new content on artificial intelligence, whole-slide and mass spectrometry imaging, and metagenomic next-generation sequencing

• Discusses the best approach for diagnostic work-up and addresses the challenges in maximizing diagnostic yield while avoiding misinterpretation of results that could lead to false positives

• Details the increasing use of molecular diagnostics in infectious disease pathology

• Provides updates on taxonomy and nomenclature across all classes of infectious microorganisms (bacteria, fungi, parasites, viruses) along with new genomic data

• Features more than 1,500 print and online-only images, including histology and gross pathology images, full-color medical illustrations, clinical photographs, and radiology images to help practicing and in-training pathologists reach a confident diagnosis

• Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care

• Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

Table Of Contents

SECTION 1: OVERVIEW

4 Standard Methods for Infectious Diseases

10 Emerging Techniques

12 Biosafety Considerations

16 Pitfalls and Artifacts

SECTION 2: VIRAL INFECTIONS

DNA VIRUSES

22 Herpes Simplex Virus 1 and 2 (HSV-1, HSV-2) Infections

28 Varicella-Zoster Virus (HHV-3) Infections

32 Epstein-Barr Virus (HHV-4) Infection

38 Cytomegalovirus (HHV-5) Infections

44 Human Herpesvirus 6 and 7 (HHV-6, HHV-7) Infections

46 Kaposi Sarcoma-Associated Herpesvirus (HHV-8) Infection

52 Herpes B Virus Infection

54 Adenovirus Infection

58 Hepatitis B and D Virus Infections

62 Parvovirus B19 Infection

66 JC Virus, BK Virus, and Other Polyomavirus Infections

72 Human Papillomavirus Infection

78 Molluscum Contagiosum

80 Smallpox, Mpox, and Other Pox Virus Infections

RNA VIRUSES

86 Arbovirus Infections

92 Zika Virus Infection

96 Ebola, Marburg, and Other Hemorrhagic Fever Virus Infections

102 Enterovirus Infections

104 Poliovirus Infection

106 Rabies Virus Infection

108 Lymphocytic Choriomeningitis Virus Infection

110 Measles Virus Infection

112 Mumps Virus Infection

114 Rubella Virus Infection

116 Human Immunodeficiency Virus Infection

120 Human T-Lymphotropic Virus Type I Infection

122 Influenza Virus Infections

126 Parainfluenza Virus Infections

128 Coronavirus Disease 2019 (COVID-19)

134 Severe Acute Respiratory Syndrome (SARS), Middle East Respiratory Syndrome (MERS), and Other Coronavirus Infections

136 Respiratory Syncytial Virus Infection

138 Rhinoviruses, Human Metapneumovirus, and Other Respiratory Virus Infections

140 Rotavirus, Norovirus, and Astrovirus Infections

142 Hepatitis A and E Virus Infections

146 Hepatitis C Virus Infection

SECTION 3: PRION DISEASES

152 Transmissible Spongiform Encephalopathies

SECTION 4: BACTERIAL INFECTIONS

158 Bacterial Classification and Diagnosis

160 Botryomycosis

162 Malakoplakia

GRAM-POSITIVE BACTERIA

164 Actinomycosis

166 Bacillus Species Infections

170 Clostridioides and Other Gram-Positive Anaerobes

174 Corynebacterium Species Infections

178 Listeria Species Infection

180 Rhodococcus Species Infection

182 Staphylococcus Species Infections

188 Streptococcus and Enterococcus Species Infections

192 Whipple Disease

GRAM-NEGATIVE BACTERIA

196 Pathologically Important Enterobacterales: Escherichia, Shigella, Salmonella, Klebsiella, and Yersinia Species Infections

204 Fastidious Organisms: Brucella, Francisella, Haemophilus, and Legionella Species Infections

210 Nonfermentative Organisms: Acinetobacter, Burkholderia, and Pseudomonas Species Infections

216 Bacteroides, Fusobacterium, and Other Gram- Negative Anaerobes

220 Bartonella Species Infections

222 Campylobacter and Vibrio Species Infections

226 Helicobacteriosis

228 Neisseria and Moraxella Species Infections

232 Pertussis

234 Intestinal Spirochetosis

236 Borrelia Species Infections

240 Leptospira Species Infection

242 Syphilis and Other Treponematoses

248 Anaplasmosis and Ehrlichiosis

252 Chlamydophila and Chlamydia Species Infections

256 Coxiella Species Infection

258 Rickettsia and Orientia Species Infections

262 Mycoplasma and Ureaplasma Species Infections

ACID-FAST BACTERIA

264 Mycobacterium tuberculosis Complex Infections

270 Leprosy

274 Buruli Ulcer

276 Mycobacterium avium Complex and Other Nontuberculous Mycobacterial Infections

280 Nocardiosis

SECTION 5: FUNGAL INFECTIONS

286 Fungal Classification and Diagnosis

MOLDS

290 Aspergillosis

296 Entomophthoramycosis

300 Fusariosis

302 Mucormycosis

306 Mycetoma

310 Phaeohyphomycosis

312 Scedosporiosis and Lomentosporiosis

314 Scopulariopsis Infections

316 Tineasis

318 Trichosporonosis

320 Superficial Mycoses

YEASTS AND YEAST-LIKE ORGANISMS

324 Blastomycosis

330 Candidiasis

336 Chromoblastomycosis

340 Coccidioidomycosis

344 Cryptococcosis

350 Histoplasmosis

356 Lobomycosis

358 Paracoccidioidomycosis

360 Pneumocystosis

364 Sporotrichosis

368 Talaromycosis

370 Rhinosporidiosis

372 Protothecosis

SECTION 6: PROTOZOAN PARASITIC INFECTIONS

376 Parasite Classification and Diagnosis

GASTROINTESTINAL AND OTHER LUMINAL PROTOZOA

380 Balantidiasis

382 Cryptosporidiosis and Other Coccidia Infections

386 Entamebiasis

390 Giardiasis

392 Microsporidiosis

394 Trichomoniasis

INTRAVASCULAR PROTOZOA

396 African Trypanosomiasis

398 Babesiosis

402 Malaria

DEEP TISSUE PROTOZOA

408 Free-Living Amebiasis

414 American Trypanosomiasis

416 Leishmaniasis

420 Toxoplasmosis

SECTION 7: HELMINTHIC PARASITIC INFECTIONS

NEMATODES

426 Ancylostomiasis and Necatoriasis

428 Angiostrongyliasis

430 Ascariasis

434 Enterobiasis

438 Gnathostomiasis

440 Human Filariasis

444 Onchocerciasis

446 Strongyloidiasis

450 Trichuriasis

454 Trichinellosis

TREMATODES

456 Clonorchiasis and Opisthorchiasis

460 Fascioliasis and Fasciolopsiasis

462 Paragonimiasis

464 Schistosomiasis

CESTODES

470 Coenurosis

472 Cysticercosis

478 Diphyllobothriasis and Hymenolepiasis

482 Echinococcosis

486 Sparganosis

SECTION 8: INFESTATIONS AND OTHER INVERTEBRATE-RELATED MALADIES

490 Tissue Damage From Arachnids and Insects

498 Myiasis

500 Scabies

502 Demodex Infestations

504 Tungiasis

Author Information

By Isaac H. Solomon, MD, PhD, Assistant Professor of Pathology, Harvard Medical School, Associate Pathologist, Department of Pathology, Brigham and Women’s Hospital, Boston, Massachusetts, Neurooncology Member, Dana Farber/Harvard Cancer Center, Boston, Massachusetts; Dan Milner, MD, MSc(Epi), MBA, Pathologist, Brigham and Women's Hospital, Assistant Medical Director, Microbiology, Brigham and Women's Hospital and Associate Professor of Pathology, Harvard Medical School, Boston, Massachusetts