The Laboratory Rat, 3rd Edition
Editors: Mark Suckow F. Claire Hankenson Ronald Wilson Patricia Foley
Table of Contents
Background of the laboratory rat1. Historical Foundations2. Taxonomy and Stocks and Strains3. Translational Potential of Rats in Research
Biology and care4. Functional Anatomy and Physiology5. Clinical Pathology of the Rat6. Reproduction and Breeding7. Assisted Reproductive Technologies and Genetic Modification in Rats8. Analysis of Behavior in Laboratory Rats9. Nutrition10. Housing and Environment
Clinical care and disease11. Medical Management and Diagnostic Approaches12. Bacterial, Mycoplasmal, and Mycotic Infections13. Viral Disease14. Parasitic Diseases15. Neoplastic Disease16. Metabolic, Traumatic, and Miscellaneous Diseases17. Anesthesia, Analgesia, and Euthanasia18. Care of Surgical and Other Fragile Models
Rats as research models19. General Experimental Techniques20. Integrating Biology with Rat Genomic Tools21. Gnotobiotics and the Microbiome22. Toxicology23. Embryology and Teratology24. Rat Immunology25. Cardiovascular Research26. Rat Models of Alcohol Use Disorder27. Rat Models of Obesity, Metabolic Syndrome, and Diabetes28. The Rate in Neuroscience Research29. Rat Models of Central Nervous System Injury30. Use of the Rat as a Model in Regenerative Medicine31. Rat Models of Infectious Disease
About the Editors
Mark Suckow Editor
Mark A. Suckow, DVM, DACLAM, is the Associate Vice President for Research, Attending Veterinarian, and Professor of Biomedical Engineering at the University of Kentucky. He is on the council on Accreditation at the Association for Assessment and Accreditation of Laboratory Animal Care International. Dr. Suckow has 25 years of experience with IACUC organization and regulatory compliance, laboratory animal medicine, research with a variety of animal models, and animal facility design and management. He is the previous editor of laboratory animal publications with CRC Press and AP/Elsevier, including Principles of Animal Research, Research Regulatory Compliance and The Laboratory Rabbit, Guinea Pig, Hamster and Other Rodents
F. Claire Hankenson Editor
F. Claire Hankenson, DVM, MS, is the Director of MSU Campus Animal Resources and Attending Veterinarian at the Michigan State University. Research interests are refinements in the case and use of animals involved in research studies, particularly rodent clinical medicine, tail biopsy evaluations and humane endpoints.
Ronald Wilson Editor
Ronald P. Wilson, VMA, MS, DACLAM, is the Professor and Chair of Comparative Medicine at Pennsylvania State University. Research interests are related to experimental surgery, pain, analgesia and anesthesia of laboratory animals.
Patricia Foley Editor
Patricia L. Foley, DVM, DCLAM, is the Director, Division of Comparative Medicine at Georgetown University.